Cell BiologybioRxiv
Piezo1 channel agonist mimics high glucose as a stimulator of insulin release
V. Deivasikamani, S. Dhayalan, R. Mughal…·P. Sukumar
This study shows that Piezo1 agonist Yoda1 stimulates insulin release from beta-cells and pancreatic islets, suggesting Piezo1's role in cell swelling-induced insulin secretion.