Author

P. Sukumar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1 Physiology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:metabolism & bioenergetics· 2 Organism:Arabidopsis· 1 Organism:bacteria (other)· 1

Frequent Co-Authors

D. J. Beech· 3 shared H. viswambharan· 2 shared R. Mughal· 2 shared A. DeLeon· 1 shared A. F. A. Moumbock· 1 shared A. M. N. Walker· 1 shared A. Matthiadis· 1 shared A. Moron· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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3 shared papersCell Biology

D. J. Beech

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Structural insights into Pseudomonas aeruginosa lysine-specific uptake mechanism for extremely low pH regulation

D. Bicer, R. Matsuoka, A. F. A. Moumbock, P. Sukumar, H. Cheruvara, A. Quigley, E. Pardon, J. Steyaert, P. J. F. Henderson, M. Caffrey, J. J. Griese, E. Nji

The paper reports the cryo-EM structure of Pseudomonas aeruginosa LysP bound to lysine and a nanobody, revealing its transport mechanism and inhibition by L-4-thialysine.

bioRxiv · May 17, 2024 · PreprintBiochemistry

PIEZO1 force sensing controls global lipid homeostasis

L. Lichtenstein, C. W. Cheng, E. L. Evans, H. J. Gaunt, F. Bartoli, E. Chuntharpursat-Bon, S. Patel, C. Konstantinou, S. Futers, M. Reay, G. Parsonage, J. Bertrand-Michel, P. Sukumar, L. D. Roberts, D. J. Beech

This study shows that endothelial PIEZO1 force sensing regulates lipid homeostasis by affecting cholesterol metabolism and excretion, with implications for hyperlipidaemia.

bioRxiv · Jul 23, 2023 · PreprintPhysiology

Paracrine role for endothelial IGF-1 receptor in white adipocyte beiging

N. J. Haywood, K. Bridge, C. Luk, N. Warmke, K. Simmons, M. Drozd, A. Moron, S. Straw, J. Scragg, J. Smith, S. Limumpornpetch, C. Ozber, C. Wilkinson, A. Skromna, N. Makava, , M. Kearney

This study shows that reducing endothelial IGF-1R in nutrient excess promotes white adipocyte beiging, increases energy expenditure, and improves insulin sensitivity through paracrine malonic acid release.

bioRxiv · Dec 1, 2021 · PreprintCell Biology

Host auxin machinery is important in mediating root architecture changes induced by Pseudomonas fluorescens GM30 and Serendipita indica

A. Matthiadis, P. Sukumar, A. DeLeon, D. Pelletier, J. Labbe, G. A. Tuskan, U. C. Kalluri

This study investigates how host auxin signaling and transport components mediate root architecture changes induced by beneficial microbes, identifying key proteins involved in the process.

bioRxiv · Aug 17, 2020 · PreprintPlant Biology

Piezo1 channel agonist mimics high glucose as a stimulator of insulin release

V. Deivasikamani, S. Dhayalan, R. Mughal, A. Visnagri, K. Cuthbertson, J. L. Scragg, T. S. Munsey, H. Viswambharan, R. Foster, A. Sivaprasadarao, M. T. Kearney, D. J. Beech, P. Sukumar

This study shows that Piezo1 agonist Yoda1 stimulates insulin release from beta-cells and pancreatic islets, suggesting Piezo1's role in cell swelling-induced insulin secretion.

bioRxiv · Oct 29, 2018Cell Biology