V. Garcia

Grapevine cell response to carbon deficiency requires transcriptome and methylome reprogramming

This study investigates how grapevine cells adapt to carbon deficiency by analyzing transcriptome and methylome changes under varying glucose conditions.

The Zinc Finger protein SlZFP2 is essential for tomato fruit locular tissue morphogenesis

The study identifies SlZFP2 as essential for tomato locular tissue morphogenesis by altering cell cycle and endoreduplication in a gel-less mutant.

Genomic signatures of adaptation in native lizards exposed to human-introduced fire ants

This study identifies genomic signatures of adaptation in native lizards exposed to invasive fire ants, showing genetic changes related to immune response and morphology.

Transplantation-based screen uncovers inducers of muscle progenitor cell engraftment across vertebrate species

The paper identifies two lipids that enhance muscle progenitor cell engraftment across zebrafish and mice by activating intracellular calcium flux.

Circadian Clock Core Component Bmal1 Dictates Cell Cycle Rhythm of Proliferating Hepatocytes during Liver Regeneration

This study shows that Bmal1 regulates the rhythmic cell cycle progression and lipid accumulation in hepatocytes during liver regeneration, with disruptions in Bmal1 leading to delayed DNA synthesis, loss of mitotic oscillation, and altered redox state.

Identification of novel human derived influenza viruses in pigs with zoonotic potential.

The paper identifies novel human-derived influenza viruses in Chilean pigs, showing zoonotic potential and antigenic drift.

Activation of proneuronal transcription factor Ascl1 in maternal liver ensures a healthy pregnancy

This study shows that Ascl1 activation in maternal liver during pregnancy supports healthy pregnancy outcomes by coordinating maternal organ adaptations and placental growth.

The Lack of Nrf2 Causes Hepatocyte Dedifferentiation and Reduced Albumin Production in an Experimental Extrahepatic Cholestasis Model

This study shows that Nrf2 deficiency leads to hepatocyte dedifferentiation and reduced albumin production in a cholestasis model.

Cancer-Induced Immunosuppression can enable Effectiveness of Immunotherapy through Bistability Generation: a mathematical and computational Examination

This paper uses mathematical models to show that cancer-induced immunosuppression can create bistability, which may be exploited for immunotherapy by tipping the system toward a cancer-free state.

Bacterially produced GABA protects neurons from degeneration

This study shows that GABA produced by bacteria protects neurons in C. elegans from degeneration, revealing a role for dietary neuroactive compounds in nervous system health.

De novo mutations drive the spread of macrolide resistant Mycoplasma genitalium: a mathematical modelling study

This study uses mathematical modeling to show de novo mutations drive macrolide resistance in M. genitalium, suggesting caution in azithromycin use for urethritis.