BiochemistrybioRxiv
A Primase-Induced Conformational Switch Controls the Stability of the Bacterial Replisome
E. Monachino, S. Jergic, J. S. Lewis…·A. M. van Oijen
This study identifies a primase-induced conformational switch that enhances the stability of the bacterial replisome by strengthening the interaction between the polymerase holoenzyme and the replicative helicase.
DOI 10.1016/j.molcel.2020.04.037