Transcriptome Dynamics Reveals Progressive Transition from Effector to Memory in CD4+ T cells.
M. S. F. Soon, H. J. Lee, J. A. Engel, J. Straube, B. S. Thomas, L. S. Clarke, P. Laohamonthonkul, C. P. S. Pernold, R. N. Haldar, C. G. Williams, L. I. M. Lansink, R. Koufariotis, V. Lakis, S. Wood, X. Chen, , A. Haque
This study uses single-cell RNA-seq and ATAC-seq to show a progressive transition from effector to memory CD4+ T cells during Plasmodium infection, with linear pathways and memory-associated gene expression.
bioRxiv · Jun 19, 2019 · PreprintImmunology