Cell BiologybioRxiv
Essential role of hyperacetylated microtubules in innate immunity escape orchestrated by the EBV-encoded BHRF1 protein
D. Glon, G. Vilmen, D. Perdiz…·A. Esclatine
This study shows that EBV's BHRF1 protein induces microtubule hyperacetylation to form mito-aggresomes, blocking IFN signaling and promoting viral survival.
DOI 10.1371/journal.ppat.1010371