Cancer BiologybioRxiv
NFATc2 enhances tumor-initiating phenotypes through the NFATc2/SOX2/ALDH axis in lung adenocarcinoma
Z.-J. XIAO, J. Liu, S.-Q. Wang…·M. P. Wong
This study identifies NFATc2 as a regulator of lung tumor-initiating cells via the NFATc2/SOX2/ALDH1A1 axis, linking it to drug resistance and poor patient outcomes.
DOI 10.7554/elife.26733