J.-W. Wang

Wounding perception by jasmonate-mediated JAZ condensation in plants

This study reveals that JAZ1 undergoes phase separation in response to wounding, facilitating rapid jasmonate signaling by reducing its interaction with MYC2 and recruiting COI1 for degradation.

Transcriptional reactivation of the tRNASer/tRNATyr gene cluster in Arabidopsis thaliana root tip (V2)

The paper identifies the tissular expression pattern of the SYY tRNA gene cluster in Arabidopsis thaliana root tips and shows its transcriptional reactivation despite DNA methylation.

A cryo-EM structure of KTF1-bound polymerase V transcription elongation complex

The paper reports a cryo-EM structure of the KTF1-bound Pol V transcription elongation complex, revealing structural features that explain its unique transcriptional properties and role in DNA methylation.

Chloroquine induces eryptosis in P. falciparum-infected red blood cells and the release of extracellular vesicles with a unique protein profile

This study shows chloroquine induces eryptosis in P. falciparum-infected red blood cells, releasing EVs with unique proteomic profiles that may activate immune pathways.

Protection against doxorubicin-induced cardiotoxicity by ergothioneine

This study investigates ergothioneine's protective effects against doxorubicin-induced cardiotoxicity in mice and finds it significantly reduces cardiac dysfunction without affecting tumor growth or chemotherapy efficacy.

Degrading intestinal DAF-2 nearly doubles Caenorhabditis elegans lifespan without affecting development or reproduction

This study shows that reducing DAF-2 in the intestine of C. elegans nearly doubles lifespan without affecting development or reproduction.

Computational approach and functional analysis of Pectobacterium carotovorum subsp. carotovorum low-molecular weight bacteriocin Carocin S2

This study predicts the structure and functional properties of Carocin S2, a bacteriocin from Pectobacterium carotovorum, and hypothesizes its hydrolytic mechanism targeting tRNA.

In vivo generation of post-infarct mouse cardiac muscle by cardiomyocyte progenitors produced with a reproducible laminin-promoted human stem cell differentiation system

This paper develops a reproducible method to generate cardiac muscle progenitors from human stem cells using laminin-221, which can form human heart muscle in vivo after transplantation.

NFATc2 enhances tumor-initiating phenotypes through the NFATc2/SOX2/ALDH axis in lung adenocarcinoma

This study identifies NFATc2 as a regulator of lung tumor-initiating cells via the NFATc2/SOX2/ALDH1A1 axis, linking it to drug resistance and poor patient outcomes.