Author

V. Shchepachev

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Organism:yeast· 2 Assay:ATAC-seq· 1 Organism:bacteria (other)· 1

Frequent Co-Authors

C. Spanos· 4 shared D. Tollervey· 4 shared S. Bresson· 3 shared A. Helwak· 2 shared J. Rappsilber· 2 shared N. Robertson· 2 shared T. W. Turowski· 2 shared D. Wright· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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4 shared papersCell Biology

C. Spanos

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4 papers

Recent·Most cited

A disease-linked lncRNA mutation in RNase MRP inhibits ribosome synthesis

N. Robertson, V. Shchepachev, D. Wright, T. W. Turowski, C. Spanos, A. Helwak, R. Zamoyska, D. Tollervey

This study shows that mutations in the lncRNA RMRP impair pre-rRNA processing and T cell activation, linking CHH to a ribosomopathy.

bioRxiv · Mar 29, 2021Cell Biology

Integrative Vectors for Regulated Expression of SARS-CoV-2 Proteins Implicated in RNA Metabolism

S. Bresson, N. Robertson, E. Sani, T. W. Turowski, V. Shchepachev, M. Kompauerova, C. Spanos, A. Helwak, D. Tollervey

The paper develops and characterizes expression constructs for 14 SARS-CoV-2 proteins involved in RNA metabolism, enabling their study in host cells.

bioRxiv · Jul 20, 2020Cell Biology

Stress-induced translation inhibition through rapid displacement of scanning initiation factors

S. Bresson, V. Shchepachev, C. Spanos, T. Turowski, J. Rappsilber, D. Tollervey

The paper shows stress-induced translation inhibition in yeast through rapid displacement of scanning initiation factors and selective mRNA degradation.

bioRxiv · May 14, 2020Cell Biology

Defining the RNA Interactome by Total RNA-Associated Protein Purification

V. Shchepachev, S. Bresson, C. Spanos, E. Petfalski, L. Fischer, J. Rappsilber, D. Tollervey

This paper introduces TRAPP, a method to identify RNA-binding proteins genome-wide, and demonstrates its application in yeast and bacteria, revealing novel RNA-protein interactions and their changes under stress.

bioRxiv · Oct 5, 2018Cell Biology