D. Tollervey

The transcriptional and translational landscape of HCoV-OC43 infection

This study maps the transcriptional and translational changes in human lung fibroblasts infected with HCoV-OC43, identifying new ORFs and ER stress response activation.

Roles of SNORD115 and SNORD116 ncRNA clusters in neuronal differentiation

This study investigates the roles of SNORD115 and SNORD116 ncRNA clusters in neuronal differentiation and their potential link to Prader-Willi syndrome.

Posttranscriptional regulation of cell wall integrity in budding yeast

The paper identifies a posttranscriptional pathway involving RNA-binding proteins that regulate cell wall gene expression in budding yeast, enhancing resistance to antifungal compounds.

Systematic mapping of small nucleolar RNA targets in human cells

The paper identifies RNA targets of box C/D snoRNAs in human cells using CLASH and FLASH techniques, revealing novel interactions with rRNA, snoRNAs, and mRNAs.

A disease-linked lncRNA mutation in RNase MRP inhibits ribosome synthesis

This study shows that mutations in the lncRNA RMRP impair pre-rRNA processing and T cell activation, linking CHH to a ribosomopathy.

Yeast Ssd1 is a non-enzymatic member of the RNase II family with an alternative RNA recognition interface

This study identifies the RNA binding interface of Ssd1, a non-catalytic RNase II family member, revealing its preference for 5UTRs of cell wall protein mRNAs and a conserved bipartite motif.

Integrative Vectors for Regulated Expression of SARS-CoV-2 Proteins Implicated in RNA Metabolism

The paper develops and characterizes expression constructs for 14 SARS-CoV-2 proteins involved in RNA metabolism, enabling their study in host cells.

Stress-induced translation inhibition through rapid displacement of scanning initiation factors

The paper shows stress-induced translation inhibition in yeast through rapid displacement of scanning initiation factors and selective mRNA degradation.

Defining the RNA Interactome by Total RNA-Associated Protein Purification

This paper introduces TRAPP, a method to identify RNA-binding proteins genome-wide, and demonstrates its application in yeast and bacteria, revealing novel RNA-protein interactions and their changes under stress.

HuD is a neural enhancer of global translation acting on mTORC1-responsive genes and sponged by the Y3 small non-coding RNA