Author

V. Simoes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Organism:yeast· 2 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

B. K. Cizubu· 2 shared N. A. Snyder· 2 shared A. Bartesaghi· 1 shared C. M. Santos· 1 shared C.-Y. Chen· 1 shared D. A. Okonkwo· 1 shared E. J. Washington· 1 shared G. Arya· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiochemistry

B. K. Cizubu

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Author profile →

2 papers

Recent·Most cited

Redox control of the deubiquitinating enzyme Ubp2 regulates translation during stress

C. M. Santos, B. K. Cizubu, D. A. Okonkwo, C.-Y. Chen, N. Maske, N. A. Snyder, V. Simoes, E. J. Washington, G. Silva

This study shows that Ubp2, a DUB, is redox-regulated during oxidative stress in yeast, controlling K63-ub chains on ribosomes and restoring translation post-stress.

bioRxiv · Apr 30, 2024Biochemistry

Redox sensitive E2 Rad6 controls cellular response to oxidative stress via K63 ubiquitination of ribosomes.

V. Simoes, L. Harley, B. K. Cizubu, Y. Zhou, J. Pajak, N. A. Snyder, J. Bouvette, M. J. Borgnia, G. Arya, A. Bartesaghi, G. M. Silva

The paper identifies Rad6 as a redox-sensitive E2 enzyme that modifies ribosomes with K63 ubiquitin during oxidative stress, linking it to translation control and stress response.

bioRxiv · Apr 22, 2021Cell Biology