Author

G. Arya

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 5 Bioengineering· 4 Cell Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:cell type annotation· 5 Approach:statistical model· 5 Assay:DNA methylation· 4 Research Focus:cell signaling & trafficking· 3 Approach:deep learning· 3 Research Focus:protein folding & dynamics· 3 Organism:bacteria (other)· 2

Frequent Co-Authors

M. G. Poirier· 5 shared C. Castro· 4 shared J. Pajak· 4 shared M. DeLuca· 3 shared W. Pfeifer· 3 shared C. M. Huang· 2 shared M. Lakadamyali· 2 shared S. Sensale· 2 shared

Activity by Year

2020-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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5 shared papersBioengineering

M. G. Poirier

Mutual co-authors in cluster

Author profile →

12 papers

Recent·Most cited

Piggybacking functionalized DNA nanostructures into live cell nuclei

G. M. Roozbahani, P. Colosi, A. Oravecz, E. M. Sorokina, W. Pfeifer, S. Shokri, Y. Wei, P. Didier, M. DeLuca, G. Arya, L. Tora, M. Lakadamyali, M. G. Poirier, C. Castro

This study demonstrates the delivery of DNA origami nanorods into live cell nuclei using an antibody against RNA Polymerase II, showing structural integrity and sub-diffusive motion within the nucleus.

bioRxiv · Dec 30, 2023 · PreprintBioengineering

An enterococcal phage protein broadly inhibits type IV restriction enzymes involved in antiphage defense

N. P. Bullen, C. N. Johnson, S. E. Andersen, G. Arya, S. R. Marotta, Y.-J. Lee, P. Weigele, J. C. Whitney, B. A. Duerkop

The paper identifies a phage protein that inhibits type IV restriction enzymes in drug-resistant enterococci, revealing how phages evolve to overcome bacterial defense mechanisms.

bioRxiv · Nov 16, 2023Microbiology

Mechanism of DNA origami folding elucidated by mesoscopic simulations

M. DeLuca, T. Ye, M. G. Poirier, Y. Ke, C. Castro, G. Arya

This paper develops a mesoscopic simulation model to study DNA origami folding, revealing hierarchical processes and kinetic differences between small and large structures.

bioRxiv · Jun 20, 2023Biophysics

Versatile Computer Aided Design of Freeform DNA Nanostructures and Assemblies

W. Pfeifer, C. M. Huang, M. G. Poirier, G. Arya, C. Castro

The paper introduces MagicDNA 2.0, a tool for automated design of freeform 3D DNA nanostructures, validated through experimental fabrication of complex geometries.

bioRxiv · Mar 30, 2023 · PreprintBioengineering

Steric Communication between Dynamic Components on DNA nanodevices

Y. Wang, S. Sensale, M. Pedrozo, C. M. Huang, M. G. Poirier, G. Arya, C. E. Castro

This paper introduces a DNA origami-based method for steric communication between dynamic components, demonstrating signal transmission through thermal fluctuations and conformational regulation.

bioRxiv · Dec 15, 2022Bioengineering

Thermally Reversible Pattern Formation in Arrays of Molecular Rotors

M. DeLuca, W. Pfeifer, B. Randoing, C.-M. Huang, M. G. Poirier, C. Castro, G. Arya

This study uses Monte Carlo simulations and experimental DNA origami rotors to show thermally reversible pattern formation in molecular rotor arrays, demonstrating order-disorder transitions and potential applications in nanomaterials.

bioRxiv · Oct 19, 2022Biophysics

Detyrosination enrichment on microtubule subsets is established by the interplay between a stochastically-acting enzyme and microtubule stability

Q. Tang, S. Sensale, C. Bond, A. Qiao, S. Hugelier, A. Arab, G. Arya, M. Lakadamyali

The paper investigates how detyrosination of microtubules occurs on specific subsets through stochastic enzyme activity and microtubule stability interactions.

bioRxiv · Sep 29, 2022 · PreprintCell Biology

Molecular Dynamics of DNA Translocation by FtsK

J. Pajak, G. Arya

This study uses molecular simulations to reveal how FtsK coordinates DNA translocation with ATPase activity through conformational changes and force generation.

bioRxiv · Jan 3, 2022Biophysics

Redox sensitive E2 Rad6 controls cellular response to oxidative stress via K63 ubiquitination of ribosomes.

V. Simoes, L. Harley, B. K. Cizubu, Y. Zhou, J. Pajak, N. A. Snyder, J. Bouvette, M. J. Borgnia, G. Arya, A. Bartesaghi, G. M. Silva

The paper identifies Rad6 as a redox-sensitive E2 enzyme that modifies ribosomes with K63 ubiquitin during oxidative stress, linking it to translation control and stress response.

bioRxiv · Apr 22, 2021Cell Biology

Viral Packaging ATPases Utilize a Glutamate Switch to Couple ATPase Activity and DNA Translocation

J. Pajak, R. Atz, B. J. Hilbert, M. Morais, B. A. Kelch, P. Jardine, G. Arya

This study identifies a glutamate switch mechanism in viral packaging ATPases that couples ATP binding to DNA translocation through conformational changes.

bioRxiv · Dec 1, 2020Biophysics

A viral genome packaging motor transitions between cyclic and helical symmetry to translocate dsDNA

M. Woodson, J. Pajak, W. Zhao, W. Zhang, G. Arya, M. A. White, P. J. Jardine, M. C. Morais

The paper shows that viral DNA packaging motors switch between helical and planar symmetry to translocate double-stranded DNA.

bioRxiv · May 23, 2020Biophysics

Dragonfly Inspired Smart Soft Robot

V. Kumar, U. Ko, Y. Zhou, J. Hoque, G. Arya, S. Varghese

This paper introduces DraBot, a dragonfly-inspired soft robot capable of locomotion, sensing, and environmental adaptation using pneumatic and microfluidic logic.

bioRxiv · Apr 28, 2020 · PreprintBioengineering