Author

V. Tobin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Marson· 2 shared E. Shifrut· 2 shared T. L. Roth· 2 shared A. Ashworth· 1 shared C. Bui· 1 shared D. Goodman· 1 shared D. N. Nguyen· 1 shared F. C. Szoka· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBioengineering

A. Marson

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2 papers

Recent·Most cited

A Cas9 nanoparticle system with truncated Cas9 target sequences on DNA repair templates enhances genome targeting in diverse human immune cell types

D. N. Nguyen, T. L. Roth, J. Li, P. A. Chen, M. M. Mamedov, L. T. Vo, V. Tobin, R. Apathy, D. Goodman, E. Shifrut, J. A. Bluestone, J. M. Puck, F. C. Szoka, A. Marson

The paper improves non-viral CRISPR-Cas9 genome editing in immune cells by using truncated Cas9 target sequences and polymer-stabilized nanoparticles, enhancing efficiency and viability.

bioRxiv · Mar 28, 2019 · PreprintBioengineering

Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function

E. Shifrut, J. Carnevale, V. Tobin, T. L. Roth, J. M. Woo, C. Bui, P. J. Li, M. Diolaiti, A. Ashworth, A. Marson

This study uses CRISPR screens in primary human T cells to identify regulators of immune function and cancer cell killing.

bioRxiv · Aug 3, 2018Immunology