V. Vidimar

RAS specific protease Induces Irreversible Growth Arrest via p27 in several KRAS Mutant Colorectal Cancer cell lines

This study shows that RRSP induces growth arrest in KRAS mutant colorectal cancer cells via p27, with varying cell fates depending on the cell line.

Inhibition of tumor growth by a novel engineered chimeric toxin that cleaves activated mutant and wild-type RAS

This paper develops a chimeric toxin that cleaves both mutant and wild-type RAS, reducing tumor burden in mouse models.