Cancer BiologybioRxiv
Inhibition of tumor growth by a novel engineered chimeric toxin that cleaves activated mutant and wild-type RAS
V. Vidimar, G. L. Beilhartz, M. Park…·K. J. Satchell
This paper develops a chimeric toxin that cleaves both mutant and wild-type RAS, reducing tumor burden in mouse models.
DOI 10.1073/pnas.2000312117