Cell BiologybioRxivPreprint
Direct monitoring of cAMP at the cardiac ryanodine receptor using a novel targeted fluorescence biosensor mouse
Filip Berisha, Konrad R. Götz, Jörg W. Wegener…·Viacheslav O. Nikolaev
The paper develops a targeted fluorescence biosensor in transgenic mice to monitor cAMP levels near RyR2 in cardiomyocytes, revealing altered cAMP dynamics in cardiac hypertrophy.
DOI 10.1101/623934