Oncogenic KRAS Requires Complete Loss of BAP1 Function for Development of Murine Intrahepatic Cholangiocarcinoma
R. K. Marcus, S. Ferri-Borgogno, A. Hosein, W. C. Foo, B. Ghosh, J. Zhao, K. Rajapakshe, J. Brugarolas, A. Maitra, S. Gupta
This study develops a mouse model showing that complete loss of BAP1 function is required for KRAS-driven intrahepatic cholangiocarcinoma.
bioRxiv · Oct 12, 2021Cell Biology