Multi-omic screening of invasive GBM cells in engineered biomaterials and patient biopsies reveals targetable transsulfuration pathway alterations
J. H. Garcia, E. A. Akins, S. Jain, K. J. Wolf, J. Zhang, N. Choudhary, M. Lad, P. Shukla, S. Gill, W. Carson, L. Carette, A. Zheng, S. Kumar, M. K. Aghi
This study identifies the transsulfuration pathway as a targetable metabolic driver of glioblastoma invasion through multi-omic analyses of engineered biomaterials and patient biopsies.
bioRxiv · Feb 23, 2023 · PreprintCancer Biology