Author

E. A. Akins

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

M. K. Aghi· 2 shared S. Kumar· 2 shared A. Zheng· 1 shared D. Wilkins· 1 shared J. H. Garcia· 1 shared J. Zhang· 1 shared K. J. Wolf· 1 shared L. Carette· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersBioengineering

M. K. Aghi

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2 papers

Recent·Most cited

BioengineeringbioRxivNov 18, 2023

An engineered glioblastoma model yields novel macrophage-secreted drivers of invasion

E. A. Akins, D. Wilkins, M. K. Aghi, S. Kumar

The paper identifies BIGH3 as a macrophage-secreted driver of GBM invasion using a 3D model and shows its inhibition reduces GSC invasion.

DOI 10.1172/jci.insight.181903

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintFeb 23, 2023

Multi-omic screening of invasive GBM cells in engineered biomaterials and patient biopsies reveals targetable transsulfuration pathway alterations

J. H. Garcia, E. A. Akins, S. Jain…·M. K. Aghi

This study identifies the transsulfuration pathway as a targetable metabolic driver of glioblastoma invasion through multi-omic analyses of engineered biomaterials and patient biopsies.

DOI 10.1101/2023.02.23.529575

humanmetabolomics

𝕏 PostBluesky