What can we learn when fitting a simple telegraph model to a complex gene expression model?
F. Jiao, J. Li, T. Liu, Y. Zhu, W. Che, L. Bleris, C. Jia
The paper fits a simple telegraph model to complex gene expression models to infer effective parameters and reveal underlying regulatory mechanisms using single-cell data from E. coli and mammalian cells.
bioRxiv · Mar 9, 2023Biophysics