Cell BiologybioRxivPreprint
Strong paracrine effects of SASP from senescence-induced severe early-onset COPD-derived fibroblasts
R. A. Meuleman, W. Timens, W. Kooistra…·R. R. Woldhuis
This study shows that SASP from senescent fibroblasts in severe early-onset COPD promotes paracrine senescence, inflammation, and ECM dysregulation in surrounding fibroblasts.
DOI 10.1101/2023.09.01.555721