Author

W. Larner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Organism:Arabidopsis· 3 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:chicken / avian· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

L. Alphey· 4 shared S. Basu· 4 shared S. Rooney· 3 shared A. Merits· 2 shared A. V. Diaz· 2 shared B. Atkinson· 2 shared C. M. Reitmayer· 2 shared E. Levitt· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersBioengineering

L. Alphey

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Author profile →

4 papers

Recent·Most cited

Optimizing CRE and PhiC31 mediated recombination in Aedes aegypti

L. Z. Carabajal Paladino, R. Wilson, P. Y. L. Tng, V. Dhokiya, E. Keen, P. Cuber, W. Larner, S. Rooney, M. Nicholls, A. Uglow, L. Williams, M. A. E. Anderson, S. Basu, P. T. Leftwich, L. Alphey

This paper improves genetic manipulation techniques in Aedes aegypti by introducing transgenic lines for Cre-mediated recombination and a plasmid-based PhiC31 integrase system for stable transgene integration.

bioRxiv · Jul 7, 2023 · PreprintBioengineering

A Zika virus-responsive sensor-effector system in Aedes aegypti

S. Basu, C. M. Reitmayer, S. Lumley, B. Atkinson, M. L. Schade-Weskott, S. Rooney, W. Larner, E. E. Montiel, R. Gutierrez-Lopez, E. Levitt, H. M. Munyanduki, A. M. E. Elrefaey, A. T. Clarke, S. Koit, E. Zusinaite, , L. Alphey

This paper describes a genetic system in Aedes aegypti mosquitoes that selectively eliminates ZIKV-infected individuals to reduce vectorial capacity.

bioRxiv · Feb 6, 2023 · PreprintBioengineering

Fake it to break it: mimicking superinfection exclusion disrupts alphavirus infection and transmission in the yellow fever mosquito Aedes aegypti

C. M. Reitmayer, E. Levitt, S. Basu, B. Atkinson, R. Fragkoudis, A. Merits, S. Lumley, W. Larner, A. V. Diaz, S. Rooney, C. J. E. Thomas, K. von Wyschetzki, K. Rausalu, L. Alphey

The paper demonstrates that mimicking superinfection exclusion in mosquitoes reduces alphavirus replication and transmission.

bioRxiv · Sep 20, 2022 · PreprintMicrobiology

Quantifying and modelling the acquisition and retention of lumpy skin disease virus by haematophagus insects reveals clinically but not subclinically-affected cattle are promoters of viral transmission and key targets for control of disease outbreaks.

B. Sanz-Bernardo, I. R. Haga, N. Wijesiriwardana, S. Basu, W. Larner, A. V. Diaz, Z. Langlands, E. Denison, J. Stoner, M. White, C. Sanders, P. C. Hawes, A. J. Wilson, J. Atkinson, C. Batten, , P. M. Beard

This study quantifies LSDV acquisition and retention by vector insects and models transmission, finding clinical cattle are key promoters of viral spread and highlighting the need for targeted control strategies.

bioRxiv · Jun 18, 2020Microbiology