Cancer BiologybioRxiv
YAP-Driven Oral Epithelial Stem Cell Malignant Reprogramming at Single Cell Resolution
F. Faraji, S. I. Ramirez, L. Clubb…·J. S. Gutkind
The paper identifies YAP-driven reprogramming of oral epithelial stem cells into tumor-initiating cells using single-cell multiomics, revealing conserved transcriptional programs linked to poor patient survival.