The Firre locus produces a trans-acting RNA molecule that functions in hematopoiesis
J. P. Lewandowski, J. C. Lee, T. Hwang, H. Sunwoo, J. M. Goldstein, A. F. Groff, N. Chang, W. Mallard, A. Williams, J. Henao-Meija, R. A. Flavell, J. T. Lee, C. Gerhardinger, A. J. Wagers, J. L. Rinn
This study shows that the Firre locus produces a trans-acting RNA involved in hematopoiesis and immune function, as demonstrated through genetic models and functional assays.
bioRxiv · May 24, 2019Immunology