The connecting cilium inner scaffold provides a structural foundation to maintain photoreceptor integrity
O. Mercey, C. Kostic, E. Bertiaux, A. Giroud, Y. Sadian, N. Chang, Y. Arsenijevic, P. Guichard, V. Hamel
The paper identifies the connecting cilium inner scaffold (CC-IS) as a structural zipper that maintains photoreceptor integrity by linking microtubules, and shows that its loss leads to retinal degeneration.
bioRxiv · Aug 27, 2021 · PreprintCell Biology