BiochemistrybioRxiv
PPM1H phosphatase counteracts LRRK2 signaling by selectively dephosphorylating Rab proteins
K. Berndsen, P. Lis, W. Yeshaw…·D. R. Alessi
This study identifies PPM1H as a phosphatase that counteracts LRRK2 signaling by dephosphorylating Rab proteins, suggesting it as a potential therapeutic target for Parkinson's disease.
DOI 10.7554/elife.50416