Cell BiologybioRxiv
A mechanical G2 checkpoint controls epithelial cell division through E-cadherin-mediated regulation of Wee1-Cdk1
L. Donker, M. J. Vliem, H. Canever…·M. Gloerich
The paper shows epithelial cells use a mechanical G2 checkpoint regulated by E-cadherin adhesions to control division in response to cell density changes.
DOI 10.1016/j.celrep.2022.111475