BiophysicsbioRxiv
Molecular mechanism for strengthening E-cadherin adhesion using a monoclonal antibody
B. Xie, A. Maker, A. V. Priest…·S. Sivasankar
This study identifies how the monoclonal antibody 19A11 strengthens E-cadherin adhesion through a salt bridge that stabilizes the strand-swap dimer interface.
DOI 10.1073/pnas.2204473119