Author

W.-Y. Lai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Evolutionary Biology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 3 Organism:Drosophila· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

C. Schlötterer· 3 shared A. M. Jaksic· 2 shared A. Aniszewska· 1 shared A. Schmidt· 1 shared A. Strömberg· 1 shared B. Hallberg· 1 shared D. E. Lind· 1 shared E. Jennische· 1 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersEvolutionary Biology

C. Schlötterer

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

ALK signalling primes the DNA damage response sensitizing ALK-driven neuroblastoma to ATR inhibition

M. Borenäs, G. Umapathy, D. E. Lind, W.-Y. Lai, J. Guan, J. Johansson, E. Jennische, A. Schmidt, Y. V. Kurhe, J. L. Gabre, A. Aniszewska, A. Strömberg, M. Bemark, M. N. Hall, J. Van den Eynden, , R. H. Palmer

This study identifies ALK signaling's role in enhancing DNA damage response in neuroblastoma, showing that combined ATR/ALK inhibition leads to sustained tumor response and differentiation.

bioRxiv · Aug 30, 2023 · PreprintCancer Biology

Pre- and post-mating reproductive isolation evolve independently during rapid adaptation to high temperature

S.-K. Hsu, W.-Y. Lai, J. Novak, F. Lehner, A. M. Jaksic, E. Versace, C. Schlötterer

bioRxiv · Nov 8, 2021 · PreprintEvolutionary Biology

Evolution of phenotypic variance during adaptation to high temperature in Drosophila

W.-Y. Lai, C. Schlötterer

This study shows that adaptation to high temperature in Drosophila reduces gene expression variance in two independently evolved populations.

bioRxiv · Jan 19, 2021Evolutionary Biology

Evolution of phenotypic variance provides insights into the genetic basis of adaptation

W.-Y. Lai, V. Nolte, A. M. Jaksic, C. Schlötterer

The paper uses gene expression variance evolution in Drosophila to infer the polygenic basis of adaptive gene expression.

bioRxiv · Jan 19, 2021Evolutionary Biology