Pharmacology & ToxicologyBritish Journal of AnaesthesiaPeer-reviewed
Propofol directly binds and inhibits skeletal muscle ryanodine receptor 1 (RyR1)
Thomas T. Joseph, Weiming Bu, Omid Haji‐Ghassemi…·Roderic G. Eckenhoff
This study shows propofol directly binds and inhibits RyR1, reducing Ca2+ release and potentially protecting against malignant hyperthermia.
7 citations