Genetic control of the human brain proteome
Chloe Robins, Yue Liu, Wen Fan…·Thomas S. Wingo
The paper identifies pQTLs for brain proteins and finds they differ from eQTLs, suggesting distinct genetic control of mRNA and protein abundance.
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Emory UniversityPrimary ORCID profile (0000-0001-5224-6895 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
3 papers
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Chloe Robins, Yue Liu, Wen Fan…·Thomas S. Wingo
The paper identifies pQTLs for brain proteins and finds they differ from eQTLs, suggesting distinct genetic control of mRNA and protein abundance.
Aliza P. Wingo, Wen Fan, Duc Minh Duong…·Thomas S. Wingo
This study identifies 114 proteins and 5 modules linked to cerebral atherosclerosis in the brain, with 23 proteins and 2 modules also associated with Alzheimer’s dementia, highlighting shared mechanisms involving synaptic signaling and myelination.
Thomas S. Wingo, Jingjing Yang, Wen Fan…·Aliza P. Wingo
The paper identifies brain microRNAs linked to late-life depressive symptoms and shows their association with cognitive decline and dementia risk.