Yue Liu

This study conducts a genome-wide association analysis of the Big Five personality traits, identifying novel genetic loci and associations with psychiatric traits.

The paper analyzes proteomic data from Alzheimer's disease brains, revealing disease-related changes not seen at the RNA level and identifying potential therapeutic targets.

This paper identifies 8 genes across 6 genomic loci associated with Alzheimer's disease risk using transcriptome-wide association study and validates them with summary Mendelian randomization.

The paper identifies pQTLs for brain proteins and finds they differ from eQTLs, suggesting distinct genetic control of mRNA and protein abundance.

This study identifies 114 proteins and 5 modules linked to cerebral atherosclerosis in the brain, with 23 proteins and 2 modules also associated with Alzheimer’s dementia, highlighting shared mechanisms involving synaptic signaling and myelination.