Author

Wendy A Bickmore

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Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Laura A Lettice· 1 shared Martin S Taylor· 1 shared Robert Hill· 1 shared Robert S Young· 1 shared William Iain Williamson· 1 shared Yatendra Kumar· 1 shared

Activity by Year

2016-2017 · peak 1/yr

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6 top collaborators · 6 mutual co-author links

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1 shared paperMolecular Biology

Laura A Lettice

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2 papers

Recent·Most cited

GenomicsGenome BiologyPeer-reviewedDec 28, 2017

Bidirectional transcription marks accessible chromatin and is not specific to enhancers

Robert S Young, Yatendra Kumar, Wendy A Bickmore, Martin S Taylor

The paper shows bidirectional transcription is common across all accessible chromatin regions, not just enhancers, and is not a reliable marker for enhancer activity.

DOI 10.1186/s13059-017-1379-8

humanChIP-seq

𝕏 PostBluesky

Molecular BiologybioRxivApr 28, 2016

Shh and ZRS enhancer co-localisation is specific to the zone of polarizing activity

William Iain Williamson, Laura A Lettice, Robert Hill, Wendy A Bickmore

The paper shows that Shh and ZRS enhancer co-localisation is specific to the zone of polarizing activity in limb buds, but proximity occurs regardless of activity.

DOI 10.1242/dev.139188

mouseexperimental assay

𝕏 PostBluesky