Synthetic BiologybioRxivPreprint
Engineering lung-sensing T cells using synthetic receptors targeting RAGE
Anjali Jacob, Caroline Whitty, Gian Luca Lupica-Tondo…·Dean Sheppard
This paper engineers T cells with synthetic receptors that activate only in the lung, demonstrating RAGE as a lung-specific target for targeted therapies.
DOI 10.1101/2025.06.06.658315