BiochemistrybioRxiv
Disulfide bridge-dependent dimerization triggers FGF2 membrane translocation into the extracellular space
F. Lolicato, J. Steringer, R. Saleppico…·W. Nickel
This paper identifies C95-C95 disulfide-bridge-mediated FGF2 dimerization as essential for membrane translocation and oligomer formation, while C77 is involved in Na,K-ATPase binding.
DOI 10.7554/elife.88579