Author

X. L. Schafer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

G. Asantewaa· 2 shared I. S. Harris· 2 shared J. Munger· 2 shared A. F. Hazel· 1 shared A. R. Huber· 1 shared A. Ruffini· 1 shared B. F. Cravatt· 1 shared C. L. Cole· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiochemistry

G. Asantewaa

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Author profile →

2 papers

Recent·Most cited

Glutathione supports lipid abundance in vivo

G. Asantewaa, E. T. Tuttle, N. P. Ward, Y. P. Kang, Y. Kim, M. E. Kavanagh, N. Girnius, Y. Chen, R. Duncan, K. Rodriguez, F. Hecht, M. Zocchi, L. Smorodintsev-Schiller, T. Q. Scales, K. Taylor, , I. S. Harris

This study shows that glutathione (GSH) is essential for lipid abundance in adult tissues, particularly in the liver, by repressing NRF2.

bioRxiv · Feb 10, 2023 · PreprintBiochemistry

Pharmacologic profiling reveals lapatinib as a novel antiviral against SARS-CoV-2 in vitro

M. H. Raymonda, J. H. Ciesla, M. Monaghan, J. Leach, G. Asantewaa, L. A. Smorodintsev-Schiller, M. M. Lutz, X. L. Schafer, T. Takimoto, S. Dewhurst, J. Munger, I. S. Harris

This study identifies lapatinib as a potent antiviral against SARS-CoV-2 in vitro, showing over 50,000-fold inhibition without toxicity.

bioRxiv · Nov 25, 2020Microbiology