F.-M. Boisvert

The Pseudogene RPS27AP5 Reveals Novel Ubiquitin and Ribosomal Protein Variants Involved in Specialised Ribosomal Functions.

The paper identifies a functional pseudogene, RPS27AP5, that produces ubiquitin and ribosomal protein variants involved in specialized ribosomal functions and transcriptional regulation.

Exploring the interactome of PML nuclear subdomains during fatty acid stress using APEX2-mediated proximity labeling

The paper uses APEX2 proximity labeling to identify the PML nuclear subdomain interactome under fatty acid stress, revealing COPII proteins and other factors involved in lipid stress responses.

CRISPR/Cas9-mediated knockout of the ubiquitin variant UbKEKS reveals a role in regulating nucleolar structures and composition.

This study shows that UbKEKS regulates nucleolar structure and composition by affecting lamin A accumulation, apoptotic regulator sequestration, and nucleolar morphology.

Subcellular distribution of PP1 isoforms in holoenzyme complexes

The paper maps PP1 isoform subcellular distribution through holoenzyme complexes using proteomic and biochemical methods, identifying c20orf27 as a novel regulatory protein and highlighting SDS22's role in PP1 localization.

Ketolysis is a metabolic driver of CD8+ T cell effector function through histone acetylation

This study identifies ketone bodies as essential for CD8+ T cell metabolism and effector function through histone acetylation regulation.

The early endosomal protein Rab21 is critical for enterocyte functions and intestinal homeostasis

This study shows Rab21 is essential for enterocyte function and intestinal homeostasis in Drosophila, with loss of Rab21 causing morphological defects, increased cell death, and inflammation.

Human Hepatocyte Nuclear Factor 4-α encodes isoforms with distinct transcriptional functions

The paper characterizes the transcriptional functions of 12 HNF4 isoforms, finding significant differences in their regulatory activity and identifying specific partners and mechanisms.