ImmunologybioRxiv
Rapid selection of HIV envelopes that bind to neutralizing antibody B cell lineage members with functional improbable mutations
O. Swanson, B. Rhodes, A. Wang…·M. L. Azoitei
The paper identifies a minimal set of mutations required for the function of a HIV bnAb and demonstrates in vitro selection of envelope immunogens that can bind to antibodies with these mutations.
DOI 10.1016/j.celrep.2021.109561