Author

A. Sanzone

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:mouse· 2 Organism:non-human primate· 2 Organism:human· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

K. Wiehe· 4 shared B. F. Haynes· 3 shared K. O. Saunders· 3 shared R. Parks· 3 shared C. B. Fox· 2 shared C. Jiang· 2 shared C. T. DeMarco· 2 shared C. W. Woods· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersImmunology

K. Wiehe

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Mutation-Guided Vaccine Design: A Strategy for Developing Boosting Immunogens for HIV Broadly Neutralizing Antibody Induction

K. Wiehe, K. O. Saunders, V. Stalls, D. W. Cain, S. Venkatayogi, J. S. Martin Beem, M. Berry, T. Evangelous, R. Henderson, B. Hora, S.-M. Xia, C. Jiang, A. Newman, C. Bowman, X. Lu, , B. F. Haynes

The paper demonstrates a mutation-guided vaccine strategy that induces HIV broadly neutralizing antibodies in mice by selecting for rare B cell lineage mutations.

bioRxiv · Nov 11, 2022 · PreprintImmunology

SARS-CoV-2 vaccination induces neutralizing antibodies against pandemic and pre-emergent SARS-related coronaviruses in monkeys

K. O. Saunders, E. Lee, R. Parks, D. R. Martinez, D. Li, H. Chen, R. J. Edwards, S. M. C. Gobeil, M. Barr, K. Mansouri, S. M. Alam, L. L. Sutherland, F. Cai, A. Sanzone, M. Berry, , B. F. Haynes

This study shows that SARS-CoV-2 vaccines induce neutralizing antibodies against SARS-CoV-1, SARS-CoV-2, and batCoVs in monkeys.

bioRxiv · Feb 17, 2021 · PreprintImmunology

Rapid selection of HIV envelopes that bind to neutralizing antibody B cell lineage members with functional improbable mutations

O. Swanson, B. Rhodes, A. Wang, X. Shi-Mao, R. Parks, A. Sanzone, M. K. Louder, B. C. Lin, N. Doria-Rose, M. Bonsignori, K. O. Saunders, K. Wiehe, B. F. Haynes, M. L. Azoitei

The paper identifies a minimal set of mutations required for the function of a HIV bnAb and demonstrates in vitro selection of envelope immunogens that can bind to antibodies with these mutations.

bioRxiv · Jan 4, 2021Immunology

The functions of SARS-CoV-2 neutralizing and infection-enhancing antibodies in vitro and in mice and nonhuman primates

D. Li, R. J. Edwards, K. Manne, D. R. Martinez, A. Schafer, S. M. Alam, K. Wiehe, X. Lu, R. Parks, L. L. Sutherland, T. H. Oguin, C. McDanal, L. G. Perez, K. Mansouri, S. M. C. Gobeil, , Petzol

This study examines SARS-CoV-2 neutralizing and infection-enhancing antibodies, showing in vitro enhancement does not always lead to in vivo disease enhancement, but can cause increased lung inflammation in monkeys.

bioRxiv · Dec 31, 2020 · PreprintImmunology