Author

Xiaotong Yang

Children's Medical CenterPrimary ORCID profile (0000-0002-8548-9954 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Xiaotong YangiD1 paper · University of Michigan

Biology Disciplines

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Biochemistry· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Edward Owusu KwartengiD· 2 shared Jacob ZielkeiD· 2 shared Ji Hyung JuniD· 2 shared Joseph Rose· 2 shared Li LiiD· 2 shared Michalis AgathocleousiD· 2 shared Baoding ZhangiD· 1 shared Changtao JiangiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCancer Biology

Edward Owusu KwartengORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Ascorbate is a physiological tumor suppressor metabolite in leukemia

Tobias Wijshake, Joseph Rose, Ji Hyung Jun, Edward Owusu Kwarteng, Xiaotong Yang, Jacob Zielke, Swetha Mahesula, Li Li, Stephen S. Chung, Stefano Comazzetto, Sean J. Morrison, Weina Chen, Michalis Agathocleous

This study shows that ascorbate deficiency in hematopoietic cells promotes leukemogenesis and identifies ascorbate as a tumor suppressor metabolite in blood cancers.

bioRxiv · Oct 21, 2026 · PreprintCancer Biology

Loss of TCA cycle turning promotes stem cell function

Yafeng Li, Joseph Rose, Edward Owusu Kwarteng, Xiaotong Yang, Jacob Zielke, Li Li, Zhiyu Zhao, Ji Hyung Jun, Michalis Agathocleous

This study shows that TCA cycle turning is not essential for stem and progenitor cell survival or proliferation and its loss enhances stem cell function in hematopoiesis.

bioRxiv · Sep 23, 2026 · PreprintBiochemistry

Glucose is a ligand-like trigger for secretion of postprandial GLP-1

Chun Mu Li, Mengqi Li, Heng-Ye Yang, Xiao Tian, Chen‐Song Zhang, Lin Zhao, Jianfeng Wu, Cixiong Zhang, Shiqi Liu, Xiaotong Yang, Xiufeng Sun, Junjie Chen, Baoding Zhang, Chuyu Yun, Jun Lin, , Sheng‐Cai Lin

This study shows glucose directly binds to glucokinase (GK) to trigger GLP-1 secretion in intestinal L cells, independent of ATP levels, and identifies GK and KATP as key players in this process.

bioRxiv · Jan 4, 2026 · PreprintBiochemistry