Systems BiologyCell SystemsPeer-reviewed
Signaling and transcriptional dynamics underlying early adaptation to oncogenic BRAF inhibition
Cameron T. Flower, C. Liu, Hui-Yu Chuang…·Forest M. White
The paper investigates early signaling and transcriptional changes in melanoma cells under BRAF inhibitor treatment, identifying SFK activation as a compensatory mechanism and demonstrating its sensitivity to co-inhibition.
8 citations