BiochemistrybioRxivPreprint
Sequence-encoded H2A.Z nucleosome dynamics control DNA unwrapping and SUV420H1 recognition
Tong Zhang, L Huang, Xuanfeng Li…·ShengQi Xiang
This study shows that H2A.Z's sequence-encoded flexibility in specific regions enhances DNA unwrapping and enables SUV420H1 recognition, revealing a mechanism linking nucleosome dynamics to epigenetic enzyme specificity.
DOI 10.64898/2026.06.10.731474