Cancer BiologybioRxiv
Methylome-based cell-of-origin modeling (Methyl-COOM) identifies aberrant expression of immune regulatory molecules in CLL
J. A. Wierzbinska, R. Toth, N. Ishaque…·D. B. Lipka
This study introduces Methyl-COOM, a method to identify cell-of-origin and CLL-specific epigenetic aberrations by analyzing DNA methylation patterns.
DOI 10.1186/s13073-020-00724-7