Cell BiologybioRxiv
Spatio-temporal analysis of human preimplantation development reveals dynamics of epiblast and trophectoderm
D. Meistermann, S. Loubersac, A. Reigner…·L. David
This study uses transcriptomic pseudotime modeling and spatial data to reveal lineage specification dynamics in human preimplantation embryos, showing TE and ICM differentiation occurs at the blastocyst stage.