MicrobiologybioRxivPreprint
Broad-spectrum antiviral activity of 3D8, a nucleic acid-hydrolyzing single chain variable fragment (scFv), targeting SARS-CoV-2 and multiple coronaviruses in vitro
G. Lee, S. Budhathoki, G.-Y. Lee…·W.-K. Kim
This study demonstrates that 3D8 scFv inhibits replication of SARS-CoV-2, HCoV-OC43, and PEDV in vitro through nucleic acid hydrolysis.
DOI 10.1101/2020.11.25.398909