Cancer BiologybioRxivPreprint
DOTA chelation through click chemistry enables favorable biodistribution of 89Zr-radiolabeled antibodies: A comparison with DFO chelation
R. Imura, Y. Kumakura, L. Yan…·N. Akimitsu
This paper compares the biodistribution of 89Zr-labeled antibodies conjugated with DOTA versus DFO chelators, finding that DOTA chelation via click chemistry provides better biodistribution profiles.