MicrobiologybioRxiv
SARS-coronavirus-2 replication in Vero E6 cells: replication kinetics, rapid adaptation and cytopathology
N. Ogando, T. Dalebout, J. C. Zevenhoven-Dobbe…·E. J. Snijder
This study compares SARS-CoV-2 and SARS-CoV replication in Vero E6 cells, finding higher viral RNA levels in SARS-CoV-2 but lower infectious progeny, and adaptive mutations in its spike protein.
DOI 10.1099/jgv.0.001453