ImmunologybioRxiv
Extracellular DJ-1 induces sterile inflammation in the ischemic brain
K. Nakamura, S. Sakai, J. Tsuyama…·T. Shichita
This paper shows that extracellular DJ-1 triggers inflammation in ischemic brains by activating TLR2 and TLR4, and that blocking DJ-1 reduces inflammation and neuronal damage.
DOI 10.1371/journal.pbio.3000939