Author

Y.-W. Lin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1 Pathology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Research Focus:cell type annotation· 1 Approach:contrastive learning· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1 Organism:virus· 1

Frequent Co-Authors

A. Neild· 1 shared A. Oddo· 1 shared A. Terskikh· 1 shared C. A. Hernandez· 1 shared C.-H. Chuang· 1 shared C.-H. Lin· 1 shared C.-H. Yang· 1 shared C.-T. Huang· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperMicrobiology

A. Neild

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cross-institutional HER2 assessment via a computer-aided system using federated learning and stain composition augmentation

C.-H. Yang, Y.-A. Chen, S.-Y. Chang, Y.-H. Hsieh, Y.-L. Hung, Y.-W. Lin, Y.-H. Lee, C.-H. Lin, Y.-C. Lin, Y.-S. Lu, Y.-Y. Lin

This paper develops a HER2 assessment system using federated learning and stain composition augmentation, achieving over 90% accuracy across two institutions with improved generalizability.

bioRxiv · Jan 17, 2024 · PreprintPathology

Allosteric inhibitors of Zika virus NS2B-NS3 protease targeting protease in super-open conformation

I. Meewan, S. Shiryaev, C.-T. Huang, Y.-W. Lin, C.-H. Chuang, A. Terskikh, R. Abagyan

The paper identifies six allosteric inhibitors of ZIKV NS2B-NS3 protease targeting a super-open conformation pocket, showing low micromolar inhibition and antiviral activity.

bioRxiv · Mar 9, 2022Pharmacology & Toxicology

Bacteriophage uptake by Eukaryotic cell layers represents a major sink for phages during therapy

M. C. Bichet, W. H. Chin, W. Richards, Y.-W. Lin, L. Avellaneda-Franco, C. A. Hernandez, A. Oddo, O. Chernyavskiy, V. Hilsenstein, A. Neild, J. C. Li, N. H. Voelcker, R. Patwa, J. J. Barr

The paper shows that eukaryotic cells internalize phages, with smaller phages being taken up more efficiently, and demonstrates this impacts phage distribution and therapy efficacy.

bioRxiv · Sep 7, 2020Microbiology