Author

Michael Chopp

Henry Ford HealthORCID 0000-0002-1948-4493Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Yi ZhangiD· 3 shared Alexandra Lucienne FoxiD· 2 shared Amy KemperiD· 2 shared Ayesha B. AlveroiD· 2 shared Gil MoriD· 2 shared Michael Millman· 2 shared Weida WangiD· 2 shared Xianshuang LiuiD· 2 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

Yi ZhangORCID

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4 papers

Recent·Most cited

NeurosciencebioRxivPreprintAug 27, 2026

Peripheral Monocyte-Derived Extracellular Vesicles Establish an Immune-Brain Communication Pathway in Alzheimer's Disease

Mingjin Wang, Weida Wang, Yanfeng Li…·Yi Zhang

The paper identifies a peripheral monocyte-derived extracellular vesicle pathway that mediates neuronal injury in Alzheimer's disease and shows IL-1β as a key mediator.

DOI 10.64898/2026.08.27.747536

mousebulk RNA-seq

𝕏 PostBluesky

Cancer BiologyMolecular OncologyPeer-reviewedFeb 13, 2026

Engineered Extracellular Vesicles Enriched with the miR-214/199a Cluster Enhance the Efficacy of Chemotherapy for Ovarian Cancer

Weida Wang, Ayesha B. Alvero, Yi Qin…·Yi Zhang

This paper shows engineered extracellular vesicles carrying miR-214-3p/miR-199a-5p enhance chemotherapy effectiveness in ovarian cancer by reversing chemoresistance and reprogramming tumor EV communication.

2 citations

mouseexperimental assay

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NeurosciencebioRxivPreprintNov 14, 2024

Mesenchymal Cell-Derived Extracellular Vesicles Ameliorate Age-Related Deficits in Working Memory as well as Brain MRI and CSF in vivo Biomarkers of Neurodegeneration in Rhesus Monkeys.

Evan C. Mackie, Chia-Hsin Cheng, Maya N. Alibrio…·Tara L. Moore

This study shows that MSC-EVs improve cognitive function and reduce neurodegeneration biomarkers in aged rhesus monkeys.

DOI 10.1101/2024.11.14.623673

non-human primateimaging

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Cancer BiologyJournal of Ovarian ResearchPeer-reviewedNov 30, 2023

Adipose-derived exosomal miR-421 targets CBX7 and promotes metastatic potential in ovarian cancer cells

Yi Zhang, Roslyn Tedja, Michael Millman…·Ayesha B. Alvero

This study identifies adipose-derived exosomal miR-421 as a regulator of CBX7 expression, promoting ovarian cancer metastasis by inducing epigenetic changes.

15 citations

humanexperimental assay

𝕏 PostBluesky